Raw Powder 99% Purity Valsartan 137862-53-4 Pharmaceutical Grade High Quality Valsartan

• Customization: Available
• Product Name: Valsartan
• CAS: 137862-53-4
• Model NO.: HMJ
• Color: White
• MOQ: 1kg
• Form: Powder
• Delivery: Express 5-7 Days Arrive
• Grade: Medicine Grade
• Package: 1kg Per Foil Bag, 10 Bags Per Carton. 25 Kg Per Dr
• Transport Package: Foil Bag/Drum
• Specification: 99%
• Trademark: HMJ
• Origin: China
• Production Capacity: 100 Tons /Month

Product Description

Product Description

          99% Purity Valsartan 137862-53-4 Pharmaceutical Grade High Quality Valsartan

What is Valsartan?

Valsartan (trade name Diovan) is an angiotensin II receptor antagonist (commonly called an ARB, or angiotensin receptor blocker), that is selective for the type I (AT1) angiotensin receptor. Valsartan is mainly used for treatment of high blood pressure, congestive heart failure, and to increase the chances of living longer after a heart attack.

Function
Valsartan is used to treat high blood pressure, congestive heart failure, and to reduce death for people with left ventricular dysfunction after having had a heart attack.
There is contradictory evidence with regard to treating people with heart failure with a combination of an angiotensin receptor blocker like valsartan and an angiotensin-converting enzyme inhibitor, with two major clinical trials (CHARM-additive and ValHeFt) showing a reduction in death, and two others (VALIANT and ONTARGET) showing no benefits, and more adverse effects including heart attacks.
In people with type II diabetes and high blood pressure or albumin in the urine, valsartan is used to slow the worsening and the development end-stage renal disease.

Application 
Valsartan blocks the actions of angiotensin II, which include constricting blood vessels and activating aldosterone, to reduce blood pressure.The drug binds to angiotensin type I receptors (AT1), working as an antagonist. This mechanism of action is different than the ACE inhibitor drugs, which block the conversion of angiotensin I to angiotensin II. Since valsartan acts at the receptor, it can provide more complete angiotensin II antagonism since angiotensin II is generated by other enzymes as well as ACE. Also, valsartan does not affect the metabolism of bradykinin like ACE inhibitors do.