Pharmaceutical Intermediates 99% Purity Esomeprazole Magnesium CAS 161973-10-0

• Customization: Available
• Product Name: Esomeprazole Magnesium
• CAS: 161973-10-0
• Model NO.: HMJ
• Color: White
• MOQ: 1kg
• Form: Powder
• Delivery: Express 5-7 Days Arrive
• Grade: Pharmaceutical Grade
• Package: 1kg Per Foil Bag, 10 Bags Per Carton. 25 Kg Per Dr
• Transport Package: Foil Bag/Drum
• Specification: 99%
• Trademark: HMJ
• Origin: China
• Production Capacity: 100 Tons /Month

Product Description

Product Description

                       Pharmaceutical Intermediates 99% Purity Esomeprazole Magnesium CAS 161973-10-0 

Product Name	Esomeprazole magnesium
Appearance	White powder
cas	161973-10-0
Assay	99%
Shelf Life	24 months when properly stored
Storage	Keep in a cool, dry, dark location

Esomeprazole is the latest in the class of agents called the protonpump inhibitors(PPIs). These drugs inhibit gastric hcl secretion by binding to hydrogen- potassium adenosinetriphosphatase (H+, K+-ATPase) in gastric parietal cells. The PPIs' ability to provide rapid symptomatic control and their demonstrated efficacy in healing erosive esophagitis have led them to be viewed as agents of choice for treating patients with gastric acid-related diseases, including gastroesophageal reflux disease(GERD), gastric ulcers, and duodenal ulcers. In addition, these agents have been shown to be effective in the treatment of Zollinger-Ellison syndrome and Barrett's esophagus. Esomeprazole is the fourth PPI to be approved for use in the United States, following omeprazole; the other available PPIs are lansoprazole, pantoprazole, and rabeprazole. PPIs have similar chemical structures and a shared mechanism of action. Esomeprazole, the S-isomer of omeprazole, is the first PPI developed as a single optical isomer. Esomeprazole has an improved pharmacokinetic profile over omeprazole (a racemic mixture of Sand Roptical isomers), resulting in more potent acid suppression.

Function:

1. For gastroesophageal reflux disease (GERD).
2.Treatment of erosive reflux esophagitis in 2. cases.
3. Long term maintenance of relapse in patients with esophagitis who have been cured.
4. Symptom control of gastroesophageal reflux disease (GERD) 4.
5. Combined with appropriate antimicrobial therapy for the eradication of Helicobacter pylori infection related peptic ulcer healing, and to prevent recurrence.
6. The risk of gastric ulcer is reduced in patients receiving continuous NSAID treatment.
7. For the treatment of liver and stomach of the chest and diaphragm, stomach burning pain.
8. For the treatment of stomachache Tunsuan, dysphagia, hiccup.

Application:

Esomeprazole magnesium (esomeprazole magnesium), also known as omeprazole, esomeprazole he left Esso chemical name, (S) - (-) -5- methoxy -2-{[(4- methyl two methoxy -3,5- -2- pyridyl) methyl] sulfinyl benzimidazole}-1H- magnesium salt, is a new type of proton pump inhibitor, can the inhibition of H+/K+-ATP activity, mainly used for the treatment of gastric acid hypersecretion induced gastric ulcer, duodenal ulcer and reflux esophagitis clinical digestive system disease.

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